Myocardial Aging, the Cardiac Atria, and BNP
نویسندگان
چکیده
منابع مشابه
Acute myocardial hypoxia increases BNP gene expression.
It is well established that cardiac failure increases cardiac B-type natriuretic peptide (BNP) expression due to myocardial stretching. However, patients with ischemic heart disease also display increased plasma BNP and proBNP concentrations despite preserved cardiac function. In this study, we examined whether acute myocardial hypoxia increases cardiac BNP expression. Surgical reduction of the...
متن کاملBNP infusion during reperfusion increases cardiac triglyceride accumulation and decreases cardiac contractility after myocardial ischemia in pigs
Introduction: Chemotherapy induced mucositis (CIM) is a frequent complication to anticancer treatments. Glucagon-like peptide-2 (GLP-2) has been suggested for treatment of CIM, unfortunately the peptide is also shown to accentuate colonic dysplasia in carcinogen treated mice. Glucagon-like peptide 1(GLP-1) is secreted simultaneously with GLP-2 from the L-cell. GLP-1 is responsible for maintaini...
متن کاملDiagnostic Value of NT-pro BNP Biomarker and Echocardiography in Cardiac Involvements in Beta-thalassemia Patients
Background N-terminal pro–B-type natriuretic peptide (NT-proBNP) is a marker to evaluate the cardiac involvement in thalassemia. We aimed to evaluate conventional and tissue Doppler echocardiography findings and its relation to plasma NT-pro BNP, Ferritin and Iron levels in beta-thalassemia patients. Materials and Methods This study performed on 164 participants equal of major beta- thalassemi...
متن کاملNHE Isoform Switching and KChIP2 Upregulation in Aging Porcine Atria
Aging increases the risk of cardiac pathologies including atrial fibrillation and can alter myocardial responsiveness to therapeutic agents. Here, seeking molecular correlates of myocardial aging processes, we performed global "whole transcript" analysis of 25,388 genes using 572,667 probes to compare the left atrial (LA) transcriptomes of young adult (9 months old) versus elderly (10 years old...
متن کاملMyocardial cell death in fibrillating and dilated human right atria.
OBJECTIVES The aim of the present study was to determine if myocytes can die by apoptosis in fibrillating and dilated human atria. BACKGROUND The cellular remodeling that occurs during atrial fibrillation (AF) may reflect a degree of dedifferentiation of the atrial myocardium, a process that may be reversible. METHODS We examined human right atrial myocardium specimens (n = 50) for the pres...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2019
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2019.08.020